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Educational Articles

Dogs + Medications & Supplements

  • SAMe is given by mouth and is used on label and over the counter to treat liver disease and other conditions. Give as directed by your veterinarian. Side effects are uncommon but may include mild stomach upset. Antidepressants, dextromethorphan, meperidine, pentazocine, and tramadol should be used with caution when given with SAMe. Inform your veterinarian of all medications, vitamins, and supplements that your pet is taking. If a negative reaction occurs, please call your veterinary office.

  • SAMe or S-adenosyl-methionine + Silybin (brand name: Denamarin®) is a combination supplement commonly used to support liver health in cats and dogs. The body uses SAMe for many important functions, such as brain, heart, hormone, antioxidant, detoxifying, and other metabolic functions. The combination of SAMe and Silybin is used to support liver and brain health. This article discusses side effects, interactions, monitoring, and storage.

  • Do you have medications stored in the bathroom cabinet, kitchen drawer, and pantry shelf? Are random bottles haphazardly tossed into the “pharmacy”? Medications are meant to help us and our pets, but they can do more harm than good if stored or administered incorrectly. You can protect your family and pets by safely handling and disposing of medications.

  • Salicylic acid topical (brand name Solva-Ker®, BioSeb®, Cerasoothe® SA, others) is an antimicrobial and antipruritic (anti-itching) agent used in the treatment of seborrheic (dry or greasy dandruff) disorders in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. It comes in cream, gel, ointment, and shampoo forms.

  • Sarolaner is given by mouth and is used to treat flea and tick infestations and has also been used off-label to treat certain types of mange and mites. Give as directed. Side effects are uncommon but may include stomach upset or neurologic symptoms. Do not use in pets with a history of seizures. If a negative reaction occurs, please call the veterinary office.

  • Seboliance (brand name Douxo®S3 SEB) is a natural extract from the pomegranate plant (Punica granatum) used to help control dandruff, reduce odor, and help hydrate dry skin in cats and dogs. Seboliance may be part of a combination product containing ophytrium. Seboliance comes in mousse and shampoo forms.

  • Selemectin is used topically on the skin to treat various parasites, both on and off label. Side effects are rare but may include hair loss at application site, gastrointestinal upset, skin reactions, or neurologic signs. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation. If a negative reaction occurs, please call your veterinary office.

  • Selegiline is typically given by mouth and is used off and on label to treat signs due to cognitive dysfunction syndrome, pituitary dependent Cushing’s disease, anxiety and certain phobias. Side effects may include vomiting, diarrhea, drooling, lack of appetite, and behavioral changes. Do not use in pets that are allergic to it, are aggressive, or in pets receiving other MAOIs, including certain tick collars. If a negative reaction occurs, please call your veterinary office.

  • Sertraline is given by mouth and is used off label to treat behavior disorders in dogs and cats. Common side effects include tiredness, vomiting, diarrhea, lack of appetite, anxiety, irritability, sleeplessness, shaking, tremors, itchy skin, or panting. Do not use in pets that are allergic to it or other SSRIs, or pets that are using MAOIs, flea/tick collars, or cisapride. If a negative reaction occurs, please call your veterinary office.

  • Ophthalmic autologous serum is a blood-derived product used to treat corneal ulcers in animals. Ophthalmic autologous serum is part of the blood and is collected directly from the patient. It is in liquid form.